Dr Tran Phuong-Thao

Dr Tran Phuong-Thao is an accomplished Medicinal Chemist (Ph.D., Seoul National University) with 15 years of specialised experience, including 77 ISI publications and 8 granted patents. Her capacity for execution is established through her role as Principal Investigator for four national projects (NAFOSTED/VINIF). Her expertise directly informs the design of these projects, integrating multidisciplinary chemistry and target-based design focusing on critical Alzheimer's pathways. The ongoing progression of her identified lead compounds towards preclinical trials confirms her strong ability to achieve translational success in novel Alzheimer's Disease (AD) therapeutics.

Her innovation directly confronts the urgent global crisis of AD, a condition where current single-target drugs offer only symptomatic relief. Leveraging over a decade of specialised expertise, her focus is a novel, multi-target drug designed to modulate several pathogenic pathways simultaneously, targeting the disease's root causes. The lead candidate demonstrates superior efficacy over clinical controls by mitigating cholinergic dysfunction and reducing characteristic plaques and tangles. Confirmed Blood-Brain Barrier (BBB) penetration combined with multi-target action promises a causal treatment with reduced side effects and simplified oral administration, significantly alleviating global healthcare burdens.